John Carew Eccles performed some of the important early experiments on synaptic integration, for which he received the Nobel Prize for Physiology or Medicine in 1963.

• 另一种常见的结果是影响突触后细胞的代谢或者基因表达。释放出来的神经递质必须通过一些机制从突触间隙中除去，才能使一次突触事件正常结束。