It was suggested that HCV infection of PBMCs could result in the change in T lymphocyte subsets, which might decrease the function of CD+4 and CD8+ cells or disable to incoordination well.

• 提示HCV感染PBMC后引起T淋巴细胞亚群发生变化，使CD+4和CD+8T细胞功能下降或不能很好地协调作用，从而成为HCV持续感染的重要原因之一。