It turns out that agmatine can inhibit PC12 cell line DNA injury induced by glutamate through block NMDA-R and improve mitochondrial function and reduce glutamate oxidative toxicity.

• 这说明胍基丁胺具有抑制PC12细胞DNA损伤的作用，其机制可能与其拮抗NMDA受体，改善线粒体功能和减轻谷氨酸的氧化毒性有关。