It is suggested that exposure to moderate experimental BUP can obviously increase the concentration of [Ca~(2+)]i in OHCs of guinea pigs,which may be one of the main causes of hearing loss by exposure to blast underpressure.

• 豚鼠暴露中等强度性BUP可引起耳蜗外毛细胞内[Ca2+]i的明显增高,且可能是听功能损害的主要原因之一。