It is known that neurohumoral factors and mechanical loads play important roles in the cardiac remodeling process, with the later having extremely great impact on cardiac hypertrophy.

• 目前已知神经体液性因素与机械性压力在心脏重塑过程中扮演著重要角色，其中机械性压力对心脏肥大的产生更是有著关键性的影响。