It is known that application of adenosine in the LDT nucleus increases sleep in vivo and directly inhibits LDT neurons in vitro by activating postsynaptic adenosine A_1 receptors.

 
  • 应用腺苷至大脑脚被盖背侧核,在活体中可增加睡眠,在实验室中可通过激活突触后膜腺苷A1受体抑制大脑脚被盖背侧核的神经元的活性。
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