It is found that the two-state model,which is used widely on the studies of protein denaturation,is not consistent with a true denaturation process.

• 通过对典型蛋白质变性实验结果的分析,发现在蛋白质变性研究领域中普遍使用的二态模型所描述的过程,与真实蛋白质变性过程并不相符。