It is an important setion of stress reaction that hypothalamic-pituitary-adrenal axis is activated.

• 下丘脑-垂体-肾上腺轴活动增强是应激反应的重要组成部分，肾上腺皮质分泌的皮质醇(Cortisol)水平可反应此轴激活的程度。