It has been shown that the CDK4-cyclinD kinase complex promotes progression entering the S of the cell cycle from GI phase.

• 研究发现，细胞周期蛋白依赖激酶(cyclin dependent kinase，CDK)与细胞周期素(cyclin)的复合物，CDK4/CDK6-cyclinD能促进细胞通过G_1期。