It has been known that autoantibodies such as AKA,APF,anti-RA33,anti-CCP and anti-Sa are valuable for the diagnosis of RA.

• 近年来,抗角蛋白抗体(AKA)、抗核周因子抗体(APF)、抗环瓜氨酸肽抗体(抗CCP抗体)、抗RA33和抗Sa等新型自身抗体的发现提高了RA诊断的敏感性和特异性;