Isothiocyanatoacetate ester is synthesized by the reaction of aminoacetic acid with carbon disulfide and ethyl chloroformate in the presence of an alkali with the overall yield of 48.

• 在碱性条件下,用氨基乙酸与二硫化碳、氯甲酸乙酯反应合成了异硫氰基乙酸乙酯,总收率为48。