Iron (Fe) plays a critical role in proliferation, and Fe deficiency results in G1/S arrest and apoptosis. Howeer, the precise role of Fe in cell-cycle control remains unclear.

• 铁元素对细胞增殖有关键的作用，铁缺乏会导致细胞停滞在G1/S期，进而发生凋亡，目前人们对铁在细胞周期的调控机制仍知之甚少。