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- Insulin receptor site 胰岛素受体部位
- Insulin receptor affinity and insulin binding were lower, too. 受体与胰岛素的高亲和力及结合率亦明显降低。
- Objective To find the site of the insulin binding with the insulin receptor via biopanning of disulfide constrained phage display heptapeptides library. 目的用肽库筛选技术寻找与胰岛素受体结合的胰岛素位点。
- Conclusion: The pathway of signal transcription after insulin receptor can be affect by leptin through PI3K pathway. PI3K途径 Part 1 Expression and Distribution of the Functional Leptin Receptor mRNA Objective Leptin receptor is a recently identified hormonal product; encoded by the diabetic(db) gene .
- A noncompetitive antagonist prevents the agonist from producing any effect at a given receptor site. 非竞争性拮抗剂可阻止激动剂在特定受体部位产生任何效应。
- Methods: The specfic 125I-insulin binding to insulin receptor with serum was measured by radioimmunoassay. 方法:放射免疫分析法测定去胰岛素血清对125I-胰岛素与胰岛素受体特异结合的影响。
- The binding Kd and Bmax value of 125 I insulin receptor were evaluated with t test and receptor binding curve was tested with Scatchard method. 12 5I 胰岛素受体结合的Kd值及Bmax值用t检验分析 ,饱和结合曲线用Scatchard分析。
- Objective To investigate the expression of insulin receptor substrate-2(IRS-2)in the liver of nonalcoholic fatty liver(NAFL)mice. 目的探讨非酒精性脂肪肝小鼠肝脏胰岛素受体底物-2(insulin receptor substrate-2,IRS-2)的表达。
- Insulin receptor substrate (IRS) molecules are key mediator in insulin signaling and play a central role in maintaining basic cellular functions. 胰岛素受体底物(Insulin Receptor Substrate，IRS)分子是胰岛素信号通路上的主要调节分子，在维持细胞正常的基础功能上扮演着重要角色。
- Masaharu K, Kanai F, Iida M, et al. Frepuency of mutations of insulin receptor gene in Japanese patients with NIDDM. Diabetes,1995,44:1081. 马立隽;王华;陈家伟;等.;中国人非胰岛素依赖型糖尿病候选基因的连锁分析
- A medicine used to treat allergies and hypersensitive reactions and colds,works by counteracting the effects of histamine on the receptor site known as H1. 用来治疗敏感症、敏感反映和伤风的药物，通过和H1受点部位组胺作用相中和而起作用。
- To study the clinical features and the role of androgen receptor ( AR ) and insulin receptor ( IR ) in auto-para endocrine control of asymmetric polycystic ovaries ( PCO ). 探讨不对称性多囊卵巢(PCO)的临床特点及雄激素受体(AR)和胰岛素受体(IR)在其发病机制中的作用。
- Patients with myotonic dystrophy, the most common form of adult-onset muscular dystrophy, have a high prevalence of insulin resistance due to disruption of the insulin receptor. 强直性肌营养不良是最常见的成年发病的肌营养不良症，由于胰岛素受体的破坏导致胰岛素抵抗的发病率很高。
- Reducing diet fat combined with endurance training could increase insulin receptor binding and TPK activity, attenuate insulin resistance and decrease body fat content to the level of the controlled rats. 减少饮食中脂肪含量同时结合耐力运动 ,可降低肥胖鼠的体脂含量至对照水平 ,既可提高细胞膜胰岛素受体结合力 ,也可提高受体后 TPK活性 ,使肥胖鼠的胰岛素抵抗得到最好的改善
- Objective: To investigate association of the G972R polymorphism of insulin receptor substrate-1(IRS-1) with essential hypertension in Mongol population of Boertala Mongol Autonomous Prefecture in Xinjiang. 目的:研究新疆博州蒙古族族胰岛素受体底物-1(IRS-1)G972R多态性同原发性高血压的关系。
- Insulin receptor substrate-1 (IRS-1) acts as a multisite docking protein that binds signal proteins and links the receptor kinase to a number of cellular functions that are regulated by insulin. 胰岛素受体底物-1(insulin receptor substrate-1, IRS-1)作为多位点的锚定蛋白，连接受体激酶和信号蛋白质，引起受胰岛素调节的许多细胞内的多种功能的活化。
- The research of binding site of insulin to insulin receptor 结合胰岛素受体的胰岛素位点研究
- There are many chemical and environmental toxins that can mimic estrogens and attach to the receptor sites also. 有许多化学和环境毒素,能模仿雌激素和附着到受体网站也。
- Insulin integrated with insulin receptor,after the functioning of signaling molecule in cells,which results in signaling transmission within cells,effectors created physiological effect. 胰岛素与其受体结合,通过一系列细胞内信号分子的作用,引起细胞内信号转导,最终到达效应器产生各种生理效应。
- The release of neurotransmitter molecules from one neuron and their attachment to receptor sites on another keep a nerve impulse moving. 神经递质分子从一个神经原释放后，附着到另一个接受点，令神经冲动保持运动的状态。
