Increased ulcerogenic effect;decreased pharmacologic effect of aspirin.Conversely, salicylate toxicity may occur in patients who discontinue steroids with concurrent high-dose aspirin therapy.

• 增加胃溃疡的作用，阿司匹林药理下降，相反中断类固醇和高剂量使用阿司匹林会出现水杨酸的毒性。