Inconsistence of glutamic acid production with yield of glutamic acid to glucose often occurs in high biotin fermentation process because of limited fermentor dissolved oxygen coefficient.

• 摘要由于受到发酵罐溶氧条件的限制，在离浓度生物素的谷氨酸发酵中往往出现产酸与糖酸转化率不协调的现象，针对这一现象，研究了二次接种叠加生物素的谷氨酸发酵工艺。