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- The results showed that the amount of HPMC and Carbomer had remarkable effects on the in vitro release of capsules. 结果表明羟丙甲纤维素与卡波姆对阻滞胶囊体外释放度影响较大。
- Objective: To investigate in vitro release characteristics of collagen double layer minipellet of erythropoietin(EPO). 目的:对红细胞生成素胶原蛋白双层微条的体外释放特性进行研究。
- Methods The floating behavior and the in vitro release characteristics of cimetidine was used as the screening indexes. 方法 以漂浮性、释药性能为指标,对处方和工艺进行单因素考察。
- Objective To study the release kinetics of theophylline from the hydroxypropyl methylcellulose (HPMC) matrix tablets in vitro release test. 目的研究以羟丙基甲基纤维素(HPMC)为基材的茶碱片剂在体外溶出的动力学规律。
- Objective: To study the preparation and the in vitro release characteristics of scutellarin sustained-release dropping pills (Scu SDP). 目的:研究灯盏花素缓释滴丸的制备方法及其体外释放特征。
- In vitro release test showed a burst release of DGR from microspheres, followed by sustained release of 50% total activity over 15 days. DGR微球的体外释放呈现两个时相,15d释放大约DGR总活性的50%25。
- Objective To investigate factors influencing the in vitro release of sulindac from the hydrogel matrix tablets and optimize the formulation. 目的 研究舒林酸亲水凝胶缓释骨架片体外释放的影响因素,筛选最优处方。
- OBJECTIVE To select the in vitro release medium for elevating the colon-specific effect of preparations prepared with konjac glucomannan. 目的筛选合适的释放介质,用于魔芋胶为载体结肠定位给药系统的体外评价。
- OBJECTIVE To prepare enteric microspheres containing thymosin, and evaluate its in vitro release profiles and in vivo bioactivity. 目的制备胸腺肽肠溶微球,并对其体外释药特性及调节免疫的体内活性进行评价。
- CONCLUSION:A good correlativity was showed between in vivo absorption and in vitro release of theophylline sustained release tablets. 结论:茶碱缓释片的体内吸收百分率与体外释放百分率间存在良好的相关关系。
- OBJECTIVE To investigate the effect of coating on Sodium ferulate porosity osmotic pump tablets in vitro release and to optimize the formulation. 目的考察包衣处方对阿魏酸钠口服微孔渗透泵控释片体外释药性质的影响,并优选最佳包衣处方。
- In vitro release of enteric capsules of Poecilobdella manillensis Lesson extract using sodium carboxy-methyl starch as disintegrant was investigated. 测定了以羧甲淀粉钠为崩解剂的菲牛蛭提取物肠溶胶囊的体外释放。
- Methods:We carried out the trial by using separated skin of rats and in vitro release transdermic instrument made by ourselves. 方法:采用大鼠离体皮肤和自制体外释放透皮装置试验。
- OBJECTIVE:To evaluate the correlativity between in vitro release and in vivo absorption of theophylline sustained release tablets. 目的:评价茶碱缓释片的体外释放与体内吸收的相关性,为其质量控制提供实验依据。
- OBJECTIVETo prepare the pulsatile contro ll ed release tablets (PCRT) of diclofenac sodium (DS) as a drug model and investig ate the influence factors in vitro release. 以双氯灭痛为模型药物,研制脉冲控释片并考察其体外释放的影响因素。
- Objective:To study the effect of composition and preparation procedure of sustained-release progesterone gel on its in vitro release rate and viscosity. 目的:研究处方的组成和制备工艺对黄体酮阴道凝胶体外释放性质和黏度的影响。
- RESULTS The plasticizer,coating level,and channeling agents were all found to have great effect on the in vitro release of Sodium ferulate porosity osmotic pump t... 结论通过对包衣处方的调整,可稳定地控释阿魏酸钠口服微孔渗透泵控释片。
- Aim:To prepare wogonin liposomes with high entrapment efficiency(EE) and desirable size,and to study in vitro release of the liposomes and its pharmacokinetics in rats. 目的:制备包封率高且粒径适宜的汉黄芩素脂质体,考察其体外释放及大鼠体内药代动力学。
- Based on the American pharmacopoeia about in vitro release degree of the long-acting phenytoin sodium capsules, we produced phenytoin sodium sustained release tablets and explored its release degree in vitro. 参照美国药典收载的“延效苯妥英钠胶囊”的体外释放速率,筛选处方,制成苯妥英钠缓释片,并进行体外释放度测定。
- W-N method and deconvolution method both indicated that the correlation between the in vitro release and the in vivo absorption in the dog of the NAF sustained-release tablet was good. 两种方法均表明NAF缓释片的体外释放与家犬的体内吸收之间相关性良好。