In this study,CPU-86017 or zh-005-zh-012 at dose of 3 mg/kg were i.v. in anaesthetized mice,and the blood pressure was monitored by arterial cannulation for 3 hours.

• v. 3 mg/kg CPU-86017或zh-005-zh-012并连续观察3 h；研究其对小鼠血压的影响;