In this review, the controversy in application of WHO classification, MDS prognosis in relation with prognostic scoring system, cytogenetics, immunophenotype and therapeutics were discussed.

• 在综述中讨论的问题包括有MDS分型存在的问题，预后积分系统与MDS，细胞遗传学与MDS预后，免疫表型特征以及治疗等与MDS预后的关系。