In this paper, we reported that anti-idiotypic antibodies (Ab2) and anti-anti-idiotypic antibodies (Ab3) were raised by the injection of monoclonal anti-HBs antibodies into syngeneic mice.

• 作者采用BALB/c鼠的抗-HBs单克隆抗体(Ab_1)作为抗原,免疫同系BALB/c小鼠,使其在自身体内产生Ab_2,观察了由Ab_2诱导的Ab_3的消长情况。