In this paper, the micronization of phytosterol particles is researched by the RESS (rapid expansion of supercritical solutions) process.

• 通过药物颗粒的微细化,降低其粒度,增大比表面积,进而提高药物颗粒的溶解度,可以有效地改善难溶药物的生物利用度。