In this paper a whole antigen vaccine of HBV is reported. The vaccine does not exclude Dane particles, It was derived from the sera of the carriers who were both HBsAg and HBeAg positive, and was of three subtypes i. e. adr adw, and ayw.

• 本文报告了一种乙型肝炎全抗原亚型疫菌,该疫苗不去除Dane颗粒,它是用HBsAg和HBeAg阳性携带者血清。 并且为adr。