In this article, main contents and technics in proteomics research were briefly introduced, and then some applications and progress of proteomics in endocrine and metabolic disease research were summarized.

• 本文简述了蛋白质组学研究的主要内容及技术平台,综述了其在内分泌和代谢性疾病包括垂体、状腺、代谢疾病以及糖尿病、胖症中的应用及进展。