In the study conducted using a fruit fly, they found that negative feedback mediated by PI3K regulates the excitability of neurons, an issue in a number of ailments that include neurofibromatosis.

• 在用果蝇的实验中，研究人员发现由PI3K介导的负反馈可以调节神经的兴奋性，这个问题在包括神经纤维瘤等许多疾病中存在。