In the rhBMP-2 treated cells, however, expression of MMP-13 was inhibited and there was a negative correla-tion between MMP13 and Col-2 expression in the first 14 days.

• 而rhBMP-2处理后的细胞中MMP-13表达水平受抑制,且MMP13和collagen2前14d表达呈明显负相关。