In the late 19th century French microbiologist Louis Pasteur discovered that injecting killed rabies virus stimulates the immune system into producing antibodies against the microbe.

• 1880年代初，法国微生物学者巴斯德发现，先将狂犬病毒杀死，再注射到动物体内，便能刺激动物的免疫系统制造对付病毒的抗体。