In our previous work, agmatine was proved to enhance morphine analgesia, inhibit tolerance to and physical dependence on morphine.

• 胍丁胺是咪唑啉受体的内源性配体,我们和国外实验室先后研究发现胍丁胺增强吗啡镇痛,对抗吗啡耐受及躯体依赖。