In last few years, two important achievements of ionization techniques in mass spec-trometry have been developed: matrix - assisted laser desorption ionization (MALDI) and electrospray ionization (ESI).

• 近年来质谱离子化技术方面有两项重要成果:基质辅助激光解吸离子化(matrix-assisted laser desorptionionization,MALDI)和电喷雾离子化(electrospray ionization,ESI)。