In conclusion,the HSV-1 gD nucleic acid vaccine was constructed successfully.The results may help to further construct multivalent nucleic acid vaccine of HSV in future.

• 本研究构建了HSV-1gD核酸疫苗，观察到其诱导小鼠产生了免疫应答，为今后HSV病毒多价核酸疫苗的研制和免疫机制的研究打下了基础。