In children the frequency of heterozygote was 35.7% and allele(+) was 17.9%,that similar to internal reports(14.7%),but much less than caucasian(43%).

• 30 8名儿童杂和突变型检出率为 35 7%25 ,等位基因 (+)频率为 17 9%25 ,与国内其它报道相近 (14 7%25 ) ,但远低于白种人群频率 4 3%25 ;