In SMCs pretreated with CsA, absorbance of cells stimulated by PE decreased by 36.67%, but it could not be further altered by the additional treatment of SNAP, Sp-8-pCPT-cGMPS and Rp-8-pCPT-cGMPS.

• VSMCs应用环胞素A预处理后；苯肾上腺素刺激诱发的VSMC吸光度降低36.；67%25；但是；上述吸光度不能被SNAP或Sp-8-pCPT-cGMPs进一步抑制或被Rp-8-pCPT-cGMPs升高。