Hyperalgesia and paraesthesia allodynia of the anim als were tested by measuring paw withdrawal latency(PWL) in response to thermal stimulation and von Frey filaments before deligation,before administration,ever y 1 hour after administration.

• 观察各组动物坐骨神经结扎前、给药前、给药后每隔1h热痛觉过敏及触觉异常的反应阈值。