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- Hydroxychloroquine is a recognized therapy for patients with pSS. 羟氯喹被公认用于干燥综合征患者。
- We report a patient with a long history of hydroxychloroquine use. 本文报道了一例长期应用羟氯喹的病人。
- The effect of hydroxychloroquine(HCQ)in the treatment of discoid lupus ery thematosus(DLE)and its side effects were observed. 观察硫酸羟氯喹HCQ治疗盘状红斑狼疮DLE的疗效并分析其副作用。
- Dr. Wasko and her associates recommend consideration of hydroxychloroquine as a standard component of treatment for rheumatoid arthritis. 博士和她的同事建议把羟基氯喹作为类风湿性关节炎标准治疗的一部分。
- Of the 4905 patients included in this analysis, 1808 (37%) reported hydroxychloroquine use at some time during the obseration period. 该研究分析的4905名患者,其中有1808名(37%25)报告曾在观测期内某段时间使用过羟基氯喹。
- In multiariable analysis, the hazard ratio for incident diabetes was 0.62 for the hydroxychloroquine group compared to the others. 在多变量分析中,羟基氯喹组与未服用该药的患者相比,糖尿病发病危险比为0.;62。
- Roughly one-third (1808) had taken hydroxychloroquine for some period of time during the study, with duration of treatment aeraging 3.1 years. 大约三分之一患者(1808)在研究的某个时期服用了羟基氯喹,平均服药时间3.;1年。
- In multivariable analysis, the hazard ratio for incident diabetes was 0.62 for the hydroxychloroquine group compared to the others. 在多变量分析中,羟基氯喹组与未服用该药的患者相比,糖尿病发病危险比为0.;62。
- In addition, the transition of hyperthyroidism to hypothyroidism occurred in the medication of SLE with steroids and hydroxychloroquine. 而甲状腺功能由亢进转变为低下发生在治疗全身性红斑狼疮而使用类固醇及氢氧奎宁的时候。
- Roughly one-third (1808) had taken hydroxychloroquine for some period of time during the study, with duration of treatment averaging 3.1 years. 大约三分之一患者(1808)在研究的某个时期服用了羟基氯喹,平均服药时间3.;1年。
- Incidence rates per 1000 patient-years of observation were 8.9 for never-users of hydroxychloroquine and 5.2 for ever-users (p <0.001). 未服用羟基氯喹的患者,糖尿病发病率为8.;9/1000人年,而服过羟基氯喹的患者糖尿病发病率为5
- In addition, we hae speculated on a new mechanism for the action of hydroxychloroquine leading to an improement in saliary flow rate. 另外,我们推测了羟氯喹的一种新作用机制,升高唾液流速。
- Putting together, we suggest that corticosteroids and hydroxychloroquine for treating SLE activity are able to control thyroid inflammation and hypothyroid function. 总之,治疗全身性红斑狼疮而使用的皮质类固醇及氢氧奎宁可能可帮助控制甲状腺发炎及甲状腺功能低下症。
- Further work is needed to explore this possibility and we intend to determine the in io effect of hydroxychloroquine on saliary cholinesterase following 6 months of therapy. 进一步的探索工作是必须的,我们试图测定6个月治疗后羟氯喹对唾液胆碱酯酶体内方面的作用。
- Antimalarial agent, such as chloroquine and hydroxychloroquine, are widely used in the treatment of autoimmune diseases in recent years, particular in rheumatoid arthritis. 近年来氯喹和羟基氯喹这两种抗疟药被广泛地应用于自身免疫性疾病的治疗,尤其是应用于类风湿关节炎的治疗。
- Poisson regression analysis reealed that the risk of incident diabetes was significantly reduced when the duration of hydroxychloroquine use was increased (P < .001). Poisson回归分析显示,如果延长服用羟基氯喹的时间,患糖尿病的风险会明显减少(P<.;001)。
- Methotrexate plus hydroxychloroquine is recommended for patients with moderate to high disease activity regardless of disease duration or poor prognostic features. 甲氨喋呤加羟氯喹的疗法是推荐给那些有中高度活动病情的患者,无论这些患者的病程长或短以及有无预后不良因素。
- Also during this time, researchers recorded incident diabetes in 54 patients who had taken hydroxychloroquine at some point s 171 patients who had neer taken the drug. 同样在这段时间,研究人员记录到曾在某个时间服用羟基氯喹的患者中有54名出现糖尿病,而从未服用该药的患者中有171名出现糖尿病。
- Combination therapy with prednisone, hydroxychloroquine and aspirin significantly improved cutaneous and arthritic symptoms, currently still in follow-up. 诊断为多中心网状组织细胞增生症,经波尼松、羟基氯喹和阿司匹林联合治疗后皮肤和关节症状显著改善,正在随访中。
- Hydroxychloroquine . 羟氯喹 。