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- Human colonic cancer cellline 结肠癌细胞系
- CLT can induce apoptosis in vitro in human colon cancer cell line CCL 229.The apoptosis inducing effect may be G1 phase specific. 克霉唑对人结肠癌细胞系CCL229有明显的凋亡诱导作用,并且能特异地诱导G1期细胞凋亡。
- ETB-2 could significantly restrain the growth of experimental human colon cancer in BALB/C nude mice and its action was of dose-dependent. ETB-2可显著抑制裸鼠人结肠癌的生长，并有一定的量-效关系；
- Objective: To study the effect of the angiogenesis inhibitor SU6668 combined with 5-Fu on liver metastasis in human colon cancer. 目的:探讨血管生成抑制剂SU6668联合5-Fu对人结肠癌肝转移的抑制作用。
- AIM: To construct a yeast two-hybrid cDNA library of hydroxycamptothecin-resistant human colon cancer cell line SW1116/HCPT in yeast cells. 目的:构建羟基喜树碱耐药结肠癌细胞株SW1116/HCPT细胞的酵母双杂交cDNA文库.
- The study included 18 rats that were gien a compound (azoxymethane) to induce colon cancer in a manner similar to human colon cancer deelopment. 该研究纳入18只大鼠为研究对象，研究人员给这些大鼠注射氧化偶氮甲烷，诱导大鼠产生与人类类似的结肠癌。
- The study included 18 rats that were given a compound (azoxymethane) to induce colon cancer in a manner similar to human colon cancer development. 该研究纳入18只大鼠为研究对象，研究人员给这些大鼠注射氧化偶氮甲烷，诱导大鼠产生与人类类似的结肠癌。
- Objective The study investigated the effect of gastrin on tyrosine phosphorylation and protein expression of focal adhesion kinase (FAK) in human colon cancer cells. 目的研究胃泌素对人结肠癌细胞信号分子黏着斑激酶(FAK)酪氨酸磷酸化和蛋白质表达的影响。
- Objective To study the expressions and clinical significance of COX-2 and nm23-h1 in human colon cancer, adenomatous polyps and normal para -cancer colon mucosa. 目的研究结肠癌、结肠腺瘤和癌旁正常结肠黏膜组织中环氧化酶2(COX-2)及nm23-h1的表达及其临床意义。
- MPA has significant inhibitory effect on the growth of human colon cancer cells,which may be related to Fas expression upregulation on cancer cell surface and G_(1) phase arrest. MPA对结肠癌细胞具有显著的抑制作用和诱导凋亡的作用,其机制可能与MPA使结肠癌细胞停滞于G1期及细胞表面Fas表达上调有关。
- Gastrin-gastrin receptor signal transduction pathway can obviously induce u-PA expression in human colon cancer cells via activating the phosphorylation of p38 kinase. 胃泌素与其受体结合后,可通过p38 MAPK信号转导通路诱导结肠癌细胞表达u-PA。
- In nude mice - animals with an inhibited immune system - engrafted with human colon cancer, the researchers first injected the engineered mesenchymal stem cells, then 5-FC. 在移植有人类结肠癌的裸鼠（没有免疫功能）中，研究人员首先注射遗传工程得到的间充质干细胞，然后注射5-FC。
- The combination of 5-fluorouracil(5FU) with p14ARF gene could increase the inhibitory function of 5FU and sensitize human colon cancer LOVO cell line to 5FU. pl4ARF基因和化疗药物5FU联合用于结肠癌LOVO细胞能够加强5FU的生长抑制作用，明显提高LOVO细胞对5FU的敏感性。
- The apoptotic rate in ETB-2A, ETB-2B and ETB-2C was significantly higher than that in control(P< 0.01). Conclusions ETB-2 could significantly inhibit the growth of experimental human colon cancer in BALB/C nude mice and its action may be dose-dependent. ETB 2A、ETB 2B、ETB 2C组凋亡率分别与对照组相比 ;差异有显著性 (P <0 .;0 1)。
- The plasmid expression vector aiming directly at cerb-B1 gene might suppress cerb-B1 gene and EGFR expression in human colon cancer LoVo cells. The new therapeutic modalities could be used in the treatment for human colon cancer. 说明本研究构建的针对cerb-B1基因的质粒表达载体可以显著抑制cerb-B1基因和EGFR蛋白在人结肠癌LoVo细胞的表达,为结肠癌的基因治疗提供了新的思路。
- Objective To evaluate the anti-tumor effects and immune mechanisms of electrochemotherapy(ECT) employing electroporation and bleomycin (BLM) in human colon cancer xenografts in nude mice. 目的 观察电穿孔技术结合博莱霉素化疗对结肠癌裸鼠移植瘤的抗肿瘤效果 ,探讨其免疫效应机制 ,为其临床应用提供实验依据。
- Objective To investigate the effects of deoxycholic acid(DCA) on the proliferation of HT-29 human colon cancer cells and the effects of berberine on activator protein-l(AP-l), cyclooxygenase-2(COX-2) expression of HT-29 cells induced by DCA. 目的 研究脱氧胆酸(DCA)对HT-29人结肠癌细胞增殖的作用及黄连素(BER)对DCA诱导下HT-29细胞激活蛋白-1(AP-1)、环氧合酶-2(COX-2)表达的影响。
- Objective To observe the combined anti-tumor effect of electroporation and bleomycin (BLM) in human colon cancer xenografts in nude mice, and to establish the experimental basis for clinical application of electrochemotherapy(ECT). 目的:观察电穿孔技术结合博莱霉素化疗对结肠癌裸鼠移植瘤的抗肿瘤效果,为本疗法的临床应用提供实验依据。
- These trisomic mice where crossed with mice that carry a mutation that causes intestinal tumors, like those seen in human colon cancers. 然后将这些三体小鼠与携带能引起肠道肿瘤的变异基因（与人类结肠癌基因类似）的小鼠进行杂交。
- Objective To study the effect of gastrin on the mRNA and protein expression of urokinase-type plasminogen activator (u-PA) in human colon cancer cells and detect the role of p38 MAPK in this process. 目的研究胃泌素对人结肠癌细胞尿激酶型纤溶酶原激活物(u-PA)mRNA和蛋白表达的影响,探讨信号分子p38 MAPK在其中的作用。
