However, until now, there has no effective algorithm dealing with the problem of unoriented blocks, as an NP-HARD problem, which is one of the two major fields in Genome rearrangements.

• 但是直到目前，基因重列的两大领域之一：无向基因重列作为一个NP-Hard问题，仍然没有一个有效的解决方法。