However, only three somatic BRCA2 mutations, 1 frameshift and 2 missense variants [6,7,9], were reported in 270 cases of primary sporadic female breast tumors.

• 然而在270例初期女性散发性乳癌的案件中，只有三例BRCA2体突变，一例移码突变及二例错义突变[6,7,9] 被报告出来。