However, during the long-time co-evolution with their hosts, symbionts have more chances to acquire unique traits in their biochemistry, physiology and secondary metabolite production.

• 本文首先简单介绍了近年共生菌次生代谢产物的结构特点与生物学功能，然后对植物内生菌、昆虫共生菌、海绵共附生菌等重要共生微生物做了重点阐述。