However hybridomas derived from the MOPC-21 myeloma ancestor contains two kinds of kappa chain transcripts, namely the correct (functional) and aberrant one, which causes the VJ rearrangement out of the normal reading frame, and results in a stop codon.

• 目前多数骨髓瘤细胞系来源于MOPC-21细胞，而且含有两种k轻链转录子，即正常(功能性)和异常轻链转录子。