Howeer, the benefit was limited to patients with a mechanical heart ale (OR=0.27), as there was no difference in the risk between the combination and OAC alone in patients with AF or CAD (OR=0.69).

• 然而，对降低动脉血栓栓塞的风险而言，联合用药优于单独使用口服抗凝药仅局限于更换机械心脏瓣膜患者(OR=0.；27)；就房颤或冠心病病人组（联合用药与单独使用口服抗凝药）没有显著差异(OR=0