Glyconate producing by fermenting has been determined by HPLC method.The effect of different chromatogram systems and eluent acidity on separation of glyconate was discussed.

• 首次应用HPLC测定发酵法制葡萄糖酸盐产品的质量，研究了不同色谱体系、流动相酸度对葡萄糖酸盐分离的影响；