Genetic variations that change the expression of CHI3L1 can influence key processes dependent on CHI3L1 levels, knocking out portions of the AKT-mediated signal pathway.

• 基因变异导致CHI3L1的表达变化可以影响依赖于CHI3L1水平的关键过程，导致部分敲除AKT介导的信号通路。