Gene chip technique for the detection of HBV genotypes and YMDD mutations is reliable and its specificity is high,it can give more information in one test and could be used for clinical application,but it is needed to improve the sensitivity;

• 基因芯片检测HBV基因型及HBV P基因区YMDD变异准确性高、特异性好,同时每次实验得到的信息量多,适合于临床开展应用,但需提高灵敏度;