From its source, the river first flows southeast to Voronezh, then southwest to its mouth. The main city on the river is Rostov on Don, its main tributary the Donets.

• 顿河从其源头起，首先向东南方流向沃罗涅日，然后向西南方向入海，河上主要城市为罗斯托夫，主要支流是顿内次河。