Following immunization with HAC60, HAC75 and HAC97 obtained through affinity chromatography, the incidence of melanoma in the mice received B16 melanoma implantation decreased, the time of tumor development delayed and tumor weight reduced.

• 亲和层析法获得的HAC60、HAC75和HAC97免疫小鼠后，小鼠移植肿瘤的发生率降低，肿瘤平均出现时间延迟，平均肿瘤重量明显减轻；