Facing his demise unless given a life saving serum, he hunts down the biologist involved in his transformation, the detective assigned to protect her, and the government forces that created him.

• 于是他不惜一切，誓要找出唯一懂得制造缓冲剂的女生物学杜玛琪。与此同时，美国军方亦派出大批人马，希望消灭简米高。