FLT3/ITD was associated with a higher early case fatality rate in AML patients and a poor prognostic in APL patients. The detection of FLT3/ITD mutation will be valuable in therapeutic efficacy evaluation and prognostic assessment in AML patients.

• FLT3/ITD阳性AML患者早期死亡率高,FLT3/ITD阳性M3患者预后差,FLT3/ITD突变检测对于AML患者疗效评价、预后估计具有重要意义。