FCM was employed to compare the effect of IM and ATO at a concentration without cytotoxicity on the inducing apoptosis of K562/MDR1,so as to analyze the pharmacology effect of IM on ATO.

• 将非细胞毒作用浓度的ATO与IM联合应用于K562/MDR1,计算此时IM的IC50以及ATO应用后的逆转倍数。