Exposure to 5-Aza-CdR induced an increased expression of the caspase 8 in the three gastric cancer cells. 5-Aza-CdR also enhanced the antitumor activity of TRAIL in three gastric cancer cells.

• 用5-Aza-CdR处理后，胃癌细胞caspase-8 mRNA表达量明显增加，且可提高细胞细胞对TRAIL的敏感性。