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- Exons of p53 p53外显子
- Expression of P53 oncogene was detected by in situ hybridization . P53基因异常表达采用原位杂交方法。
- The results of PCR-SSCP analysis showed that 2 out of 4 SPA with abnormal exon 8 of p53 gene. PCR-SSCP分析显示,本研究的4例涎腺多形性腺瘤组织中,2例出现第8外显子异常电泳带; 1例出现第6外显子异常条带。
- There were the positive results of PCR SSCP in the exon 7 of p53 of BEAS TE, exon 8 of p53 of BEAS STE, and exon 1 of p16 of both exposed cells, but there were only the suspicious positive results showed in the exon 1 of both exposed cells. SSCP结果阳性的有BEAS TE细胞p5 3第 7外显子 ,BEAS STE细胞p5 3第8外显子以及这二种细胞的p16基因第 1外显子 ; Ki ras基因第 1外显子的结果仅为可疑阳性。
- Expression level of p53 is higher in A-BCC group than in NA-BCC group. A-BCC组的p53阳性表达等级较NA-BCC组的高。
- Aim:Expression of P53 protein and prognostic indicator in brest carcinoma. 目的 观察P~(53)蛋白在乳腺癌中的表达及预后相关的病理参数之间的关系。
- The Study of P53 Expression In Squamous Cell Carcinoma and Keratoacanthoma. 鳞癌及角化棘皮瘤中P53表达的研究
- Methods: Five exons of RHO gene in probands of four adRP Chinese families were amplified by PCR, and the products were directly sequenced. 方法:通过聚合酶链反应(PCR)对4个显性视网膜色素变性家系先证者视紫红质基因的5个外显子进行扩增,扩增产物进行直接测序。
- In all bladder cancers, 25.8% had mutations in exon 7, but no mutation in exon 1.No positive SSCP was found in the two exons of control group. 62例膀胱组织中,第7外显子突变为25.;8%25,第1外显子未发现突变,在对照组织中,未发现有指示突变的异常带型;
- The (GCG)6(GCA)3GCG in the first exon of PABPN1 has no mutation either in normal family members or in patients. 患者和表现正常的成员的PABPN1不存在(GCG)_6(GCA)_3GCG的突变。
- The polyadenylation signal (pA) within the vector defines the final exon of the endogenous transcription unit. 在载体中,多聚腺苷酸信号限制到内源转录单位的最后一个外显子。
- The positive rate of P53 protein expression in LMS was clearly higher than that of UL (P<0.01)and BLM (P<0.01). LMS组P5 3蛋白表达阳性率显著高于UL组 (P <0 .;0 1)和BLM组 (P <0
- No SNP was found in the fifth and the sixth exon of PIT-1 gene in these three breeds pigs, and one SNP was found in the fourth exon. 3个猪种PIT、-1基因的第五和第六外显子中均未发现SNP;
- Objective To investigate the expression of p53,Bcl 2 and Ki 67 protein in cutaneous basal cell carcinoma (BCC). 目的 研究和探讨p5 3、Bcl 2及Ki 6 7在皮肤基底细胞癌 (BCC)中的表达情况 ,为临床诊断及治疗提供帮助。
- Objective To screen the point mutation at the codon 54(GGC54GAC) in the first exon of the mannan binding lectin (MBL) gene in Hans from Guangdong. 目的对广东地区汉族人群的甘露聚糖结合凝集素结构基因第一外显子第54位密码点突变(GGC54GAC)进行初步筛查。
- Results The positive expression of P53 protein was found in 18 of 42 specimens of BCC(42.85%). 3结果 42例皮肤基底细胞癌中 ;18例 P5 3蛋白表达阳性 ;阳性表达率为 42 .;85%25 ;
- A study on the loss of heterozygosity at 17p13.3 and abnormal expression of p53 protein in gastric carcinoma. 胃癌组织17p13.;3杂合性丢失及p53蛋白异常表达的研究
- S: (1) The positive rate of P53 in EC was 31.6%,significantly higher than those in EH and BPE (P < 0.05). P53蛋白在EC组中的阳性率为31.;6%25;明显高于EH组和BPE组(P<0
- SU-DHL-9 had homozygous deletion of p16 gene. Meanwhile, SU-DHL-1 and Daudi cell lines had mutation of the second exon of p16 gene. GAC in codon 30 mutated into AAC. SU-DHL-9有p16基因的纯合缺失,而SU-DHL-1和Daudi细胞系有p16基因的第二外显子的突变,SU-DHL-1的测序结果为密码子30的GAC突变为AAC,密码子35的GCT突变为ACT,密码子40与41之间插入了一个C;
- AIM:To explore gene mutations of p53 gene in samples of keloid pedigrees and the relation of keloid onset. 目的:探讨瘢痕疙瘩家系样本有无p53基因突变以及与瘢痕疙瘩发病的关系。 方法:实验标本来自南方医科大学南方医院整形外科2005年收集的A和B两个瘢痕疙瘩家系。