您要查找的是不是:
- Efflux pump inhibitor 外排泵抑制剂
- Suggest metabolites for the proton pump inhibitor Omeprazole. 指出质子泵抑制剂奥美拉唑的代谢物。
- Keywords fluoroquinolone;Stenotrophomonas maltophilia;pulsed field gel electrophoresis;mutant prevention concentration;quinolone - resistance determining regions;efflux pump inhibitors; 氟喹诺酮药物;嗜麦芽寡养单胞菌;脉冲场凝胶电泳;防耐药变异浓度;靶位基因;主动外排泵抑制剂;
- Esomeprazole,a new proton pump inhibitor,is the S-i somer of omeprazole. 艾司奥美拉唑是一种新型的质子泵抑制剂,它是奥美拉唑的S-型光学异构体。
- Objective:To explore the role of efflux pump in drug resistance to fluoroquinolones in Stenotrophomonas maltophilia. 目的:探讨主动外排泵在嗜麦芽寡养单胞菌对氟喹诺酮类药物耐药中的作用。
- The drug-resistance mechaniam of shigella caused by producing inactived enzyme,changing cell walls,target site structure and active efflux pump. 志贺菌的耐药机制主要是产生灭活酶、细胞壁的改变、主动外排以及作用靶位结构的改变。
- ABSTRACT Objective To investigate the role of efflux pump of Acinetobacter baumannii mutant strains against fluoroquinolones. 目的探讨主动外排泵在鲍曼不动杆菌诱导突变株对氟喹诺酮类药物敏感性的影响。
- Proton pump inhibitor (PPI) Losec seems to be the best medication for the elderly upper gastrointestinal bleeding. 质子泵抑制剂洛赛克治疗老年上消化道出血疗效显著。
- P-glycoprotein is an ATP-driven efflux pump which transport a wide variety of structurally diverse compounds from the cell interior into the extracellular space. 糖蛋白是一个能量依赖性转运蛋白,能将许多结构不同的化合物逆向转运出细胞。
- For patients with ulcer bleeding and low-risk endoscopic stigmata, high-dose oral proton pump inhibitor therapy is suggested. 对溃疡出血和低危内窥镜显小孔的患者,建议应口服大剂量质子泵抑制剂。
- Objective To evaluate the therapeutic effectiveness of the proton pump inhibitor (losec) to prevent gastroenteric reaction induced by chemotherapy. 摘要目的观察质子泵抑制剂(洛赛克)在化疗过程中对胃肠道反应的预防保护作用。
- Conclusion The proton pump inhibitor combined routine antinauseants can prevent gastroenteric reaction induced by chemotherapy and improve the QOL of patients. 结论质子泵抑制剂联合止吐剂临床应用,可以预防化疗所致的胃肠道反应并能改善化疗病人的生活质量。
- The acrAB locus encode the efflux pump AcrAB,which confers multidrug tolerance,controlled by the regulon marRAB. Mutation in the gyrase and topoisomerase IV lead to fluoroquinolones resistance, mainly arise in gyrA and parC genes. AcrAB外流泵系统的合成有多重耐药调节子 (marRAB)调控 ,AcrAB与多种抗生素的耐药有关。 拓扑异构酶 (topoisomerase)的突变主要与氟喹诺酮类药物的耐药性有关 ,突变主要发生在gyrA ,parC基因上
- Objective To investigate the effect of proton pump inhibitor(PPI)combined H2 receptor antagonist(H2RA)in the treament of portal hypertensive gastropathy(PHG). 目的探讨质子泵抑制剂(PPI)联合H2受体拮抗剂(H2RA)在治疗门脉高压性胃病(PHG)中的作用。
- The mechanism of bacterial efflux pumps is one of the important factors resulting in bacterial multidrug resistance. 细菌耐药性,尤其是多重耐药问题日益严重,给临床治疗带来极大的困难。
- Abstract Objective:AIM To investigate the effects of proton pump inhibitor(PPI)Omeprazole on tachycardia-induced acute atrial electrical remodeling in rabbits. 目的:探讨质子泵抑制剂奥美拉唑对心房快速起搏所致家兔心房电重构的影响。
- It suggested that the level of resistance of isolates would be related to selecting pressure of fluoroquinolones and induced gene mutations of DNase and topoisomerase IV could not activate AcrAB efflux pump system. 提示临床分离的鸡大肠杆菌O 78的耐药水平与喹诺酮类药物的选择性压力有关,它诱导了DNA旋转酶和拓扑异构酶IV的基因突变,可能不能激活A crAB外输泵。
- Objective To study the mechanism of multiple-antibiotic-resistance in clinical isolates of Shigella and to detect the distribution and expression of active efflux pump gene acrAB-tolC. 目的研究志贺菌患者分离株的多重耐药机制。 方法检测志贺菌中有无主动外排系统acrAB-tolC结构基因acrAB-tolC在临床分离菌株中的分布;
- The overexpression of membrane proteins functioning as drug efflux pumps is one of the main mechanisms for multidrug resistance of Candida albicans. 膜转运蛋白高表达导致多药抗药是白念珠菌抗药性产生的最重要机制之一。
- To investigate multiple-antibiotic-resistance mechanism in Escherichia coli, the distribution of active efflux pump gene, acrAB, were determined by PCR, Southern bolt, and its expressions by RT-PCR, in clinical strains of Escherichia coli. 为了研究临床分离多重耐药大肠杆菌的耐药机制,我们采用PCR和Southernblot检测大肠杆菌主动外排系统AcrAB结构基因acrAB在临床分离菌株中的分布并用RT-PCR测定其mRNA表达水平。