EGFR and P16 gene take an important part of signal transduction of laryngeal carcinoma. simultaneously,EGFR higher expression and homazygous absence or mutation of P16 present in laryngeal carcinoma.

• EGFR和P16基因在喉癌细胞信号转导中起重要作用,同时,在喉癌细胞中呈现EGFR高表达和P16基因的突变或纯合子的缺失。